SP Scientific Products company News and Trends items

SP Scientific Products (SP) has announced one of the world's largest simultaneous installation of commercial lyophilizers for use in the production of diagnostic tests. The order for SP lyophilizers was made last year by a leading global healthcare company in response to the need for an increase in SARS-CoV-2 testing.

SP announces the launch of its SP Hull LyoStar® 4.0 R&D and process development freeze dryer designed and built to enhance speed to market of biopharmaceutical products, such as biological drugs. The new LyoStar 4.0 results from SP’s extensive lyophilization expertise and represents a significant advancement in freeze dryer engineering.

The LyoConstellation provides the flexibility in that it could be used aseptically within a GMP environment as well as for lyophilization development in relation to the small-scale manufacture of parenteral products. SP Scientific have a strong heritage in freeze-drying technology and offer a range of proprietary technological innovations such as ControLyo® controlled nu...

This new global partnership brings together best in class freeze drying and vial washing/sterilizing technologies from SP Scientific with the advanced and comprehensive vial and syringe filling capabilities of Lab-i-DOSiTECNO. Oriol Casòliva, CEO of Lab-i-DOSiTECNO commented, “The geographic synergies of SP Scientific and Lab-iDosiTECNO working together will enable u...

The BioCool V40 is the only controlled rate freezer that does not require expendable liquid nitrogen and the associated pumping, re-filling, and storage challenges posed by a cryogenic liquid. The BioCool simply plugs into a standard electrical outlet and quietly provides low temperature cooling to -40º C. The magnetic stirrer and vortex breaker of the BioCool V40 ensure...

The US National Cancer Institute’s Natural Product Repository is one of the world’s largest, most diverse collections of natural products containing over 230,000 unique extracts derived from plant, marine, and microbial organisms that have been collected from biodiverse regions throughout the world. This national resource is available to the US research community for the...

Incorporating a stainless steel chamber with mechanically refrigerated walls - Vapor Trap provides highly efficient vapor trapping without the time-consuming inconvenience, expense and hazard of expendable coolants such as liquid nitrogen or dry ice. As well as being incredibly simple to use and offering superior vapor trapping capabilities, Vapor Trap has been designed ...

Clinical laboratories play a vital role in the healthcare industry as about 80% of the clinician’s diagnoses are based on laboratory analysis with a range of tests carried out on clinical specimens, to obtain information about the health of a patient to aid in diagnosis, treatment and prevention of disease. These departments commonly perform automated quantitative tests ...

The Quality by Design (QbD) approach to producing lyophilized products is increasingly being adopted in the pharmaceutical and biopharmaceutical industries. In the manufacturing environment, this translates into leveraging a sound understanding of operations to design a manufacturing process with defined multivariate parameter ranges that produce acceptable product quali...

To explain the many benefits of its ground-breaking Line of Sight approach to freeze-drying, SP Chief Marketing Officer - Ian Whitehall will make a technical presentation* on April 2nd entitled 'From Formulation to Full Commercialization - Scaling Up with Line of Sight'. The presentation will take place in Technical Theatre 5 from 2:00PM – 2:30PM. Mr. Whitehall commen...

Dimethyl sulfoxide (DMSO) is an important polar aprotic solvent that dissolves both polar and non-polar compounds and is miscible in a broad range of organic solvents as well as water. Because of these properties it is widely used as a universal sample storage solvent. However, samples dissolved in DMSO cannot be as easily recovered compared to other solvents, as it is v...

Dimethyl sulfoxide (DMSO) is an important polar aprotic solvent that dissolves both polar and non-polar compounds and is miscible in a broad range of organic solvents as well as water. Because of these properties it is widely used as a universal sample storage solvent. However, samples dissolved in DMSO cannot be as easily recovered compared to other solvents, as it is v...

Using LyoSpeed™ technology on Genevac EZ-2 Elite and Series 3 HT evaporators, HPLC fractions can be automatically concentrated to a few milliliters, then frozen and rapidly lyophilized to produce a diffuse dry powder, which can easily be re-dissolved or weighed out. Traditional concentration of reverse-phase HPLC fractions to dryness in a Genevac evaporator is a fast ...

LyoConstellation is a Line of Sight™- enabled freeze-drying system with very powerful refrigeration, delivering an expanded equipment capability and a large process space. This allows the development of highly aggressive cycles and the mapping of the furthest reaches of theoretical design space for a formulation. When handling high-value active pharmaceutical ingredient ...

The goal of Line of Sight is to bring pharmaceutical products safely and quickly to market by enhancing product and process knowledge at every step and substantiate the process within a data-rich environment. The new sp-lineofsight.com microsite provides site visitors with relevant background and data supporting utilization of this approach as well as detailed informati...

Building upon over 50 years of freeze-drying experience, the LyoS 2.0 control system delivers unmatched process control for all stages of the cycle, from freezing to primary and secondary drying. User definable process alarms protect your valuable product and automated system tests to ensure your lyophilizer is running optimally. All of this in a software package that ...

Designed for both freeze-drying experts and novices, the interactive seminar format of Lyoscopedia 2019 provides a platform for exciting discussions about freeze-drying topics relevant to both academic research and industrial applications. In addition to four talks covering the basic principles of freeze drying, the Lyoscopedia 2019 program includes talks on analytica...

This webinar, which takes place on January 24 2019, will focus on ways to jumpstart your development effort, including the use of Manometric Temperature Measurement and SMART™ process analytical technology (PAT) tools in the LyoCapsule™ freeze dryer. Illustrated by several examples, Dr. Braun will discuss wall temperature adjustment, amorphous and crystalline formulation...

Cytotoxic drugs are used widely in the treatment of cancers as well as other diseases. Antibody drug conjugates are a class of highly potent therapeutic drugs used for treating targeted cancerous tumors. These chemotherapeutic drugs can be 100- to 1000-times more toxic than traditional anticancer agents and extreme care should be taken when handling. Working in conjun...

Forensic investigations often use the sensitivity and identifying power of Mass Spectrometry (MS), typically with solid phase extraction and evaporation as part of the sample preparation process. Blood and urine analysis are widely used for forensic investigations into drug-related deaths, drug-facilitated crimes and in the clinical assessment of alcohol and drug consump...

Presented by renowned freeze-drying expert - Dr Jeff Schwegman there will be two sessions of this free webinar entitled "Scale-Up, Cycle Transfer, and Maximum Throughput Capability" on 31st October 2018. Topics to be covered in the webinar will include critical parameters in scale-up and cycle transfer, scale-up strategy, mapping studies, dryer configuration, determining...

Unlike some systems that use expensive, expendable cryogens such as liquid nitrogen or carbon dioxide to control temperature, the AirJet XR requires only house-compressed air to control temperature. When dry air passes through the AirJet XR it is cooled by the mechanical refrigeration system and heat input is precisely regulated to control the temperature of the air stre...

Designed for pharmaceutical and biotech labs, the AdVantage Pro has comparable shelf temperature uniformity (+/- 1.0°C) and system vacuum control performance to larger production freeze dryers, but in a convenient benchtop package. At only 26 in (66 cm) wide, the Advantage Pro requires a minimal amount of your valuable bench space, yet enables product to be safely proces...

To enable all users to achieve excellent results every time, the EZ-2 has been made easier to use than a conventional rotary evaporator. In addition to accommodating many more samples, it can operate entirely unattended. Using Genevac’s patented Dri-Pure® sample protection system – the EZ-2 can dry your samples without cross-contamination and sample loss due to solvent b...

The Omnitronics™ controller is driven by an industrial-grade programmable logic controller (PLC), which provides extreme versatility while remaining intuitively easy to use. Incorporating a full colour touch screen the controller enables users to configure set-up of a vast range of important parameters on their Benchtop Pro freeze dryer. The controller’s main screen d...

A major factor in determining the speed of evaporation is the rate at which heat enters the sample. As well as the temperature of the heat lamps or thermal medium, the thermal conductivity of any materials in between must also be taken into consideration. Removing solvents such as DMSO or water from microplates has traditionally been time-consuming because of the poo...

The objective of vial washing is to remove particulate matter and microorganisms. Traditional vial washers employ many moving parts, and in particular, needles to direct wash water into the vials, which can lead to chipped vials and unwanted particulate matter. SP PennTech washers have only two moving parts inside the washing chamber, and do not use needles, minimizing ...

The Ultra is a true workhorse system - flexible and small enough to fit into a laboratory but with larger shelf and condenser capacity to enable those involved in small-scale production or scale-up research to process larger batches. Control options are available to provide cGMP-compliant data monitoring and automation applications for 21CFR11 requirements. With the U...

Configured with a 5-litre 316 stainless steel evaporation vessel – the Rocket Synergy 4D is proven to offer productive automated removal of solvent for labs running kilo scale preparative chromatography equipment. Traditionally such labs have relied upon using several rotary evaporators to remove the large volumes of solvent from sample fractions. This time consuming...

A Genevac Rocket Evaporator was chosen to dry the samples because of its high-volume sample capacity, unique technology that eliminates cross contamination due to sample bumping and automated monitoring of temperature and pressure to prevent sample degradation. Employing Genevac’s proprietary SampleGenie™ technology, with the Rocket Evaporator, enabled TUM scientists to ...

To eliminate these risks, the IGP system purges the air from the HT Series 3 evaporator using an inert gas prior to commencing the evaporation process. As the highest risk of explosion exists at the beginning of the evaporation, when there is a mixture of solvent vapour and oxygen in the evaporation chamber, the IGP may be ‘locked on’ ensuring all users are automatically...

Sébastien Chanlon, Production Manager of the Eurofins Biomnis Analytical Chemistry Business Unit, commented “My department employs a wide range of analytical tools including LC/MS/MS, GC/MS, ICP/MS, HPLC and UPLC for diagnostic testing of human samples for therapeutic drugs monitoring, drugs of abuse, metabolic disorders, oligoelements and vitamin deficiencies. A lot of ...

Mr. Larkin brings to SP broad experience as a senior executive having spent the last 27 years in commercial and executive leadership roles in the medical device industry. Most recently he served as Vice President and General Manager for Becton Dickinson's US Diabetes Care business and prior to that was Senior Vice President and General Manager of LifeCell Corporation. Be...

On 21st February 2018, Dr Michael Pikal, recently retired Professor of Pharmaceutical Technology at the University of Connecticut will present 'The Power of Simple Modelling to Facilitate Scale Up of Freeze Drying Processes: Primary Drying’ an important topic that will look at the identification and evaluation of the critical experimental freeze-drying data input and the...

In new born infants, tandem Liquid Chromatography Mass Spectrometry (LC/MS/MS) is a widely used analytical technique to identify metabolic neonatal disorders which include aminoacidemia’s, urea cycle disorders, organic acidurias, and fatty acid oxidation disease. Sample preparation techniques widely used in neonatal screening include solvent extraction, acid derivati...

Unlike many traditional freeze dryers that employ coil condensers, Freezemobile freeze dryers use a smooth walled condenser which enables fast defrost & removal of ice for faster turn-around time and also alleviates vapor port ice blockages other systems are prone to. Offered in 25 and 35-liter condenser sizes, the frrezemobile provides the largest capacity commercial...