Achieving transfection-grade DNA from automated Maxi, Mega, and GigaPrep scales using Biotage® PhyPrep

Cut prep time by up to 40%

Biotage® PhyPrep is the first platform to enable fully walkaway, automated plasmid purification at Maxi-, Mega-, and Giga-scale, eliminating manual bottlenecks and producing transfection-grade DNA ready for immediate use.

In this application note, you will learn how automated purification with Biotage® PhyPrep streamlines plasmid preparation while dramatically reducing hands‑on time. The workflow supports plasmid production at concentrations up to 1 mg/mL, with DNA that is low in endotoxins and predominantly supercoiled.