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Micronisation

Leila Dietrich
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Dec Group offers customized DPI manufacturing solutions

A dry-powder inhaler (DPI) is a device that delivers medication such as corticosteroids to the lungs through inhalation. DPIs are commonly used to treat respiratory diseases such as asthma and chronic obstructive pulmonary disease. The powdered substances used for this purpose need to have a strict Particle Size Distribution (PSD) in the range of 1-5 microns to ensure that the drug constituent part is deposited deep into the lungs and the peripheral airways.

Dec Group recently completed several projects in this field and can offer their customers a comprehensive contained/sterile solution for the handling and processing of potent powders used for DPIs, starting from the incoming materials handling, to fully contained micronization, blending and inhaler filling, using their newly developed and patented generation of jet mills, the MC DecJet® series.

From their extensive expertise in the powder handling industry, Dec Group can provide a wide range of technical support to their customers for their specific process development and optimization. Dec Group also offers testing facilities to make sure to obtain the required results or to master scale-up challenges.

Dec Group’s MC DecJet® series offers a complete line of scalable spiral jet mills that provide highly efficient and versatile solutions for micronizing, not only for powders in the pharmaceutical industry but as well in the chemical, cosmetic and food industries. The MC DecJet® systems range from MC DecJet® 30, for R&D purposes to MC DecJet® 400, suitable for micronizing up to 300 kg/hr, and are supplied in accordance with US/EU Good Manufacturing Practices (GMP) guidelines.

Visit Dec Group at this years INTERPHEX, New York from 2 – 4 April, Booth 3071

MC DecJet® 150
MC DecJet® 150

Contained Micronization

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