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Extensive Offering for Cryogenic Sample Homogenization

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Lab mills for grinding with liquid nitrogen or dry ice

Reproducible grinding and homogenizing of solid sample materials is an important step of sample preparation. However, not all materials can be successfully processed at room temperature. Some samples, for example, must not get too warm while others are very elastic and just deform when being submitted to size reduction.

The ideal solution for thoroughly homogenizing these types of samples is cryogenic grinding which involves the use of dry ice or liquid nitrogen as grinding aid. Their cooling effect makes the sample brittle and lets it break more easily; moreover, negative effects of the frictional heat generated by the grinding process are eliminated so that, for example, volatile sample components, which are frequently the object of analysis, are preserved.

RETSCH offers a wide range of laboratory mills suitable for cryogenic grinding of a large variety of materials. The CryoMill was developed specifically for this application and features an integrated cooling system. The continuous cooling of grinding jar and sample with liquid nitrogen ensures a highly effective grinding process. The operation is very safe for the user as he doesn’t come into contact with LN2 at any point.

Further RETSCH mills which can be used for cryogenic grinding thanks to appropriate accessories include the Ultra Centrifugal Mill ZM 200, Mixer Mill MM 400, Cutting Mill SM 300, Knife Mill GM 300 and Mortar Grinder RM 200. RETSCH has produced a number of application videos for cryogenic grinding which can be watched on the website

RETSCH is the leading solution provider for neutral-to-analysis sample preparation and characterization of solids. On the basis of more than 100 years of experience RETSCH develops innovative size reduction and sieving equipment which is characterized by excellent performance, operating convenience, safety and a long lifetime.

Extensive Offering for Cryogenic Sample Homogenization

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