CLAM-2000 - Fully automated sample preparation module for LCMS

For pharmaceutical and medical departments and biological analysis laboratories

Shimadzu, one of the world leaders in analytical instrumentation, has released a new and unique fully automated sample preparation module (RUO) connected online for LCMS to the four major clinical research markets in Europe, i.e. Germany, France, Italy and Spain. The CLAM-2000 (Clinical Laboratory Automated sample preparation Module) automates the pretreatment of blood or other biological samples before LCMS analysis. It is designed for customers handling blood samples in pharmaceutical departments, medical departments or biological analysis laboratories dealing with issues of variability in analytical results or infection risk.

In recent years, there has been considerable progress in the use of mass spectrometers (MS) in the clinical research field due to their highly sensitive detection and high specificity as well as the possibility of multiplexing analysis without the risk of cross reactions inherent to immuno-assays. Mass spectrometry enables direct detection of disease related biological compounds in blood, urine or other biological samples, measurement of trace concentration levels of drugs as well as other applications. However, the bottleneck is still sample preparation which is often tedious, involves risk of errors and increases the risk of contamination of people dealing with sample preparation.