Freeze Drying Monitoring & Control

Operating in conjunction with SP Scientific''s LyoStar 3 development freeze dryer the LyoFlux® 200 enables users to better understand instantaneous changes in water vapor mass flow, and thus the sublimation rate for a given product during freeze-drying. This is of particular importance for products processed in atypical container systems including syringes and PCR microplates.

The LyoFlux® 200 has also been shown to provide highly sensitive end point determination for both primary and secondary drying; continuous mass balance determination; real-time calculation of average product temperature and resistance as well as assessment of heat transfer coefficients for vials (Kv) or other containers. The LyoFlux® 200 can be used for performance testing and design space calculations on a freeze dryer.

Compact in design the LyoFlux® 200 can be installed and utilized on all sizes of developmental freeze dryers. For further information please contact SP Scientific on +1-845-255-5000 or shireen.scott@spscientific.com.

Physical Sciences Inc. is located in Andover, MA, USA, and provides contract research and development services in a wide diversity of technical areas to both government and commercial customers. Interests span basic research to technology development, with an emphasis on applied research.

SP Scientific is a leading manufacturer of laboratory to production scale freeze dryers / lyophilizers, centrifugal evaporators and concentrators, thermal control system and glassware washers. The company sells its products under well-known brands including VirTis, Hull, FTS Systems, Genevac, and National-Hotpack. SP Scientific has ISO 9001:2008 registered production facilities in the USA and Europe.